Systemic lupus erythematosus – diagnostic and treatment challenges
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A 5.5-year-old Bischon Frise with a history of shifting-leg lameness, fever, weight loss, lethargy and anorexia was referred for a second opinion. The diagnostics led to a suspicion of SLE. A thorough physical examination, haematology, biochemistry, vector-borne diseases testing, urinalysis, x-ray of thorax, abdomen, carpal and tarsal joints, ultrasound of abdomen, synovial fluid and CSF fluid examination was performed to exclude differentials. A positive ANA test with four major and two minor clinical signs confirmed the diagnosis. The prednisone monotherapy administered proved to be sufficient.
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Bennett D. Immune-mediated and infective arthritis. 2010. In: Ettinger SJ, Feldman EC, editors. Textbook of veterinary internal medicine. St. Louis, Saunders Elsevier, 743-9.
Fournel C., Chabanne L., Caux C., Faure J.R., Rigal D., Magnol J.P., Monier J.C. 1992. Canine systemic lupus erythematosus. Lupus, 1: 133-9. https://doi.org/10.1177/096120339200100303
Marks S.L., Henry C.J. 2000. In: Bonagura JD editor. Kirk’s current veterinary therapy XIII: small animal practice 13rd edition. Philadelphia: Saunders, 514-16.
Webb A.A., Taylor S.M., Muir G.D. 2002. Steroid-responsive meningitis-arteritis in dogs with noninfectious, nonerosive, idiopathic, immune-mediated polyarthritis. J Vet Intern Med 16: 269-73. DOI: 10.1111/j.1939-1676.2002.tb02368.x